Identification and Characterization of a Unique Subpopulation ( CALLA / CD I 0 - Negative ) of Human Neutrophils

نویسندگان

  • Robert T. McCormack
  • Robert D. Nelson
  • Dennis E. Chenoweth
چکیده

We have previously demonstrated that human neutrophils synthesize the common acute lymphoblastic leukemia antigen (CAILA/CDiO). To determine whether CALLA/CD1Opositive and -negative neutrophils have similar or distinct functional attributes. we sorted normal peripheral blood neutrophils for CAIIA/CD1O expression and compared their chemotactic ability. Surprisingly. the low-frequency (-5%). CAILA/CD1O-negative neutrophils displayed a dramatically heightened chemotactic response to activated

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تاریخ انتشار 2005